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Friday, June 22, 2012

Alternative splicing problem


[please click on the comic for higher resolution]

Thanks to Dr. Ece Gamsiz for her cartoon idea!



Info for non-science readers
Alternative splicing is a process by which the exons of the RNA produced by transcription of a gene are reconnected in multiple ways during RNA splicing. The resulting different mRNAs may be translated into different protein isoforms; thus, a single gene may code for multiple proteins. There are numerous modes of alternative splicing observed, of which the most common is exon skipping. In this mode, a particular exon may be included in mRNAs under some conditions or in particular tissues, and omitted from the mRNA in others. 
Source: [Wikipedia].